翻訳と辞書 Words near each other ・ Trans-2,3-dihydro-3-hydroxyanthranilate isomerase ・ Trans-2-decenoyl-(acyl-carrier protein) isomerase ・ Trans-2-enoyl-CoA reductase (NAD+) ・ Trans-2-enoyl-CoA reductase (NADPH) ・ Trans-2-Methyl-2-butenal ・ Trans-2-Phenyl-1-cyclohexanol ・ Trans-3-Methyl-2-hexenoic acid ・ Trans-3-Methyl-4-decanolide ・ Trans-3-Methyl-4-octanolide ・ Trans-4,5-Epoxy-(E)-2-decenal ・ Trans-acenaphthene-1,2-diol dehydrogenase ・ Trans-aconitate 2-methyltransferase ・ Trans-aconitate 3-methyltransferase ・ Trans-acting ・ Trans-acting siRNA ・ Trans-activating crRNA ・ Trans-activation response element (TAR) ・ Trans-Afghanistan Pipeline ・ Trans-African Highway network ・ Trans-Alaska Pipeline Authorization Act ・ Trans-Alaska Pipeline System ・ Trans-Alay Range ・ Trans-Allegheny Lunatic Asylum ・ Trans-Am Production Cars ・ Trans-Am Series ・ Trans-Amazonian Highway ・ Trans-Amazonian Railway ・ Trans-American Footrace ・ Trans-Anatolian gas pipeline ・ Trans-Anatolian Pipeline Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Trans-activating crRNA ： ウィキペディア英語版 Trans-activating crRNA In molecular biology, trans-activating crRNA (tracrRNA) is a small ''trans''-encoded RNA. It was first discovered in the human pathogen ''Streptococcus pyogenes''. In bacteria and archaea, CRISPR/Cas (clustered, regularly interspaced short palindromic repeats/CRISPR-associated proteins) constitute an RNA-mediated defense system which protects against viruses and plasmids. This defensive pathway has three steps. First a copy of the invading nucleic acid is integrated into the CRISPR locus. Next, CRISPR RNAs (crRNAs) are transcribed from this CRISPR locus. The crRNAs are then incorporated into effector complexes, where the crRNA guides the complex to the invading nucleic acid and the Cas proteins degrade this nucleic acid. There are several pathways of CRISPR activation, one of which requires a tracrRNA which plays a role in the maturation of crRNA. TracrRNA is complementary to and base pairs with a pre-crRNA forming an RNA duplex. This is cleaved by RNase III, an RNA-specific ribonuclease, to form a crRNA/tracrRNA hybrid. This hybrid acts as a guide for the endonuclease Cas9, which cleaves the invading nucleic acid.〔 ==See also== *CRISPR 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Trans-activating crRNA」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.